Bashar al-Assad’s regime in Syria is crumbling, affecting various regional players including Russia, Iran, Turkey, and the United States. Each actor faces potential shifts in influence, with Russia and Iran’s support waning, while Turkey seeks to reclaim its role amidst the upheaval. U.S. strategy remains uncertain as Presidents Joe Biden and Donald Trump have differing views on intervention. The impending transition of power in the U.S. raises questions about future involvement in Syria, amid Israel’s strategic interests. The geopolitical landscape is in flux as the Syrian conflict continues to evolve.