Researchers at Radboudumc have developed a revolutionary microscope that allows for real-time visualization of biological processes, including atherosclerosis development. This world-first technology combines high detail imaging with live cellular activities, previously thought incompatible. Using graphene to protect biological samples from electron beam damage, investigators can freeze processes temporarily and resume them for observation. This advancement opens pathways for new drug development and may lead to less invasive treatments for patients with calcified heart valves, with projects like a heart valve on a chip set to begin in 2025.