Iran’s President Masoud Pezeshkian has emphasized the necessity of addressing the United States as a principal adversary, advocating for patience in dealings with enemies. Following Donald Trump’s presidential victory, Pezeshkian acknowledged the need for Iran to manage its relationship with the U.S. independently. The remarks come amid unresolved tensions surrounding the 2018 U.S. withdrawal from the nuclear agreement and reinstatement of sanctions. Iranian officials are wary of prior U.S. policies and await guidance from Supreme Leader Ali Khamenei regarding future negotiations with the incoming Trump administration.