The UK government plans a clinical trial to evaluate the use of puberty blockers for children questioning their gender, amid a backdrop of heightened referrals and evolving medical guidelines. Health Secretary Wes Streeting has committed to establishing the trial to address the lack of evidence on the safety and effectiveness of these drugs. This undertaking presents ethical dilemmas, including the risks of withholding treatment from young people in distress and concerns over long-term implications for their health. Parents, experts, and institutions are closely monitoring the outcome as the debate continues.

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