The French health magazine ‘Prescrire’ has released its annual list of 106 medications recommended for avoidance due to their greater risks than benefits. The review calls for regulatory action by the end of 2024 to remove these drugs, highlighting concerns over effectiveness and potential adverse effects, including psychological issues linked to certain treatments. Among the notable medications discussed are Ozempic and Zyban, with critiques on their efficacy and safety profiles. The publication urges healthcare professionals and health authorities to prioritize patient safety and review the approval status of these drugs.